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SPRINGFIELD — Developer Peter A Picknelly, along with Springfield city officials, on Thursday unveiled a proposal to build a new Hampden County courthouse on a 14.5-acre site along the Connecticut River north of the Memorial Bridge. The proposal, which also includes housing and a marina, comes with a pricetag of $475 million.

The plans, unveiled at a press conference, call for a four-story, 210,000-260,000-square-foot courthouse; an 11-story residential apartment building with 120-180 units; and a 50-slip marina on the waterfront and a space for an outdoor restaurant.

The proposal hinges on whether the state decides to replace the troubled Roderick L. Ireland Courthouse on State Street. The state is exploring potential new sites and the cost of building a new courthouse; the existing facility has been plagued by health concerns.

Springfield Mayor Domenic Sarno said that if the state decides to build a new courthouse, the proposed riverfront site would be the ideal location.

Sarno, Picknelly, and Tim Sheehan, Springfield’s chief development officer, all said that a development of this size and with its various components could be a catalyst for growth along the river and in the North End of the city, similar to what the Basketball Hall of Fame has done for the area south of the Memorial Bridge.

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SPRINGFIELD Colliers Capital Markets announced that it has been retained by MassDevelopment, to sell 1550 Main Street, the 128,900 square-foot office building in Springfield’s downtown corridor.

Colliers Executive Vice President Jeanne Pinado will lead marketing efforts of 1550 Main, with Vice President Rob Schlesinger providing additional support, and the firm will issue a call for offers in mid-July.

The five-story office building is 97% leased and underwent a complete $9 million renovation in 2010. Capital improvements included creating a high-quality building entrance with an open atrium with 70-foot ceilings, as well as building an outdoor plaza and improving landscaping, elevators, restrooms and more.

Formerly a federal courthouse, 1550 Main St. is home to tenants such as the administrative offices for Springfield Public Schools, the United States General Services Administration, and BayState Health. The building has a 103-space below grade garage and connects via a pedestrian skywalk to the 28-story Tower Square, an office, retail, hotel and parking complex. MassDevelopment purchased 1550 Main from the federal government in 2009 and revitalized the campus to position it as a Class A office building with an expansive public plaza as part of an economic development initiative.

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NORTHAMPTON — HONEY, a recreational cannabis dispensary, located in the former home of Sierra Grille, will stage its grand opening on July 9 at 1 p.m.

Visitors can enjoy all day music, fresh popped kettle corn, and performances by the local hula hoopers, wing dancers, stilt walkers, and aerialists. There will be a fire performance at 8:30 p.m.

HONEY is owned and operated by Volkan Polatol and Kevin Perrier. In opening HONEY Northampton, Polatol and Perrier have teamed up with HONEY Brands, originally founded in California, which produces full spectrum, distilled cannabis oil in vape cartridges.

“We are thrilled to partner with the HONEY brand,” Perrier said. “It’s telltale black-and-gold packaging has become synonymous with the best cannabis hash oil on the market today. And now, consumers on the East Coast can try it for themselves. We’re also proud to be able to make the HONEY hash oils from our own facility at Wemelco Industries in Easthampton.”

In addition to HONEY vapes, the dispensary also carries the highest-testing flower and a huge selection of brands from across the state. The location’s innovative LED tunnel, color-changing displays, and chill playlist all create a relaxed, club vibe, and budtenders are on hand to give expert advice on all products.

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LEE — Evan Collins has joined Lee Bank as a mortgage originator and will be working out of the Pittsfield branch.

Colins was previously employed as a sales associate at Piretti Real Estate and Stone House Properties. He has been involved in real estate sales in Berkshire County for seven years and said he is looking forward to exploring a different side of the local real estate market in his new position.

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AMHERST — UMass Amherst has received a $10 million, five-year award from the Centers for Disease Control and Prevention (CDC) to create the New England Center of Excellence in Vector-Borne Diseases (NEWVEC).

The UMass-based center is one in a group of regional centers of excellence designated by the CDC to reduce the risk of vector-borne diseases – such as Lyme disease and West Nile virus – spread by ticks, mosquitoes and other blood-sucking arthropods across the U.S.

Stephen Rich, vector-borne disease expert and professor of microbiology, is the principal investigator on the project and will serve as the executive director of NEWVEC, whose three-pronged mission will integrate applied research, training and community of practice to prevent and reduce tick- and mosquito-borne diseases in New England. NEWVEC aims to bring together academic communities, public health practitioners and residents and visitors across the Northeast.

“We’re really excited about building this community of practice and embracing all the stakeholders in the region who need to know how to do things like reduce ticks and mosquitoes on school properties and public spaces. It is also important to inform the public on best practices to keep ticks and mosquitoes from biting people and their pets,” Rich said. “Part of that mission entails training public health entomologists — undergraduate, master’s and Ph.D.-level students — who are going to be the next generation of people confronting these challenges.”

Infectious disease epidemiologist Andrew Lover, assistant professor in the School of Public Health and Health Sciences, will serve as deputy director of the center, with co-principal investigator Guang Xu at UMass Amherst, and co-principal investigators at Northern Vermont University, the University of Maine, University of New Hampshire, University of Rhode Island and Western Connecticut State University.

“This center fills a critical gap in responses to vector-borne disease in the region,” said Lover, who aims to apply his prior work with regional malaria elimination programs to build strong networks across the Northeast region. “As pathogens and vectors don’t pay attention to borders, coordination across states is essential for public health response. Among other things, we’ll develop practical public health tools to understand how and where people are most likely to interact with ticks, which will then allow for well-targeted and efficient health programs.”

His lab also will provide technical assistance to directly support local health practitioners in optimizing vector surveillance strategies and designing operational research to improve program effectiveness.

Xu, research professor of microbiology, will be responsible for the center’s pathogen testing core and will conduct applied research in the evaluation of tick suppression approaches.

Rich notes that blood-sucking ticks transmit more vector-borne diseases than any other arthropod in North America, accounting for some 400,000 cases of Lyme disease alone every year. “And at least a half-dozen other pathogens are associated with the blacklegged tick,” commonly known as the deer tick, he adds. “It’s kind of a silent epidemic.”

The researchers say it’s critical to attack the problem on all fronts by using applied research projects to reduce tick populations and optimize personal protection and control products, and by training public health students and workers, as well as individuals.